giuliana-rancic

While she has been very open about her struggles with infertility, Giuliana Rancic and husband Bill Rancic are still hoping to bring home a sibling for their 2-year-old son Duke. The candid E! News star, 40, says she has only one frozen embryo left.

“This could be our last shot,” Giuliana told Life & Style. “We’re keeping our fingers crossed that everything works out.”

Although she’d love to have another child, the Fashion Police star – who received major backlash last week after making an offensive comment on TV – is sure to count her blessings.

“If I don’t ever have another kid, I have to remind myself that I’m very fortunate to have what I have,” she shared.

Giuliana went through three rounds of IVF treatments before finding out she had breast cancer. The couple put their plans to start a family on hold while Giuliana underwent a double mastectomy.

After beating cancer, the Rancics turned to Delphine, the surrogate who would later deliver Duke, but Delphine suffered a miscarriage with their second child in 2014.

“We struggled for so many years to have a baby, and now that it has come true we really enjoy each and every moment with Duke,” Giuliana shared with Celebrity Baby Scoop.

She added: “This year has been incredible and also tough. I wouldn’t say this has been the most challenging year, because my most challenging year was when I had breast cancer. However, it has been a challenging time, because I love my baby so much and want to make sure I’m doing everything I can to ensure he’s safe, healthy, and happy. Bill and I have given it our all this year and it’s been a lot of work. At the same time, it’s been incredibly rewarding and we’ve loved every minute of it.”